Special Call For Papers
American Journal of Physiology -
Heart and Circulatory Physiology

Translational Physiology

Vascular Signaling by Free Radicals

Topic: Vascular Signaling by Free Radicals

Deadline for Submission: May 1, 2003

The American Journal of Physiology: Heart and Circulatory Physiology is looking for manuscripts to be submitted specifically relating to Vascular Signaling by Free Radicals. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are now known to play a broader role in cardiovascular function signaling and apoptosis. In disease states elevated levels of ROS and RNS may impair vasomotor responses and contribute to the development of atherosclerosis. They may also mediate responses to disease by signaling hypertrophy, stimulating collateral blood vessel growth, and activating nuclear transcription. The purpose of this call for papers is to highlight novel roles of ROS and RNS in both physiological and pathophysiological functions in the cardiovascular system. Papers describing new methods for detecting ROS/RNS in biological systems are also sought. As a result we hope to shed new light on the emerging role of oxidants in cardiovascular regulation.

All papers will receive expedited review. Please make sure they are labeled for the Special Call. Accepted manuscripts will be published under a distinct heading and will receive special attention and handling. Only those papers not requiring extensive revision will be published under this call. If you currently have a manuscripts on this topic that has already been submitted and would like it to be included in the Special Call, please contact Dr. David Harder, Editor (Phone: 414-456-5613, Fax: 414-456-6421). Guest Editors for this Special Call will be Drs. Balaraman Kalyanaraman and David Gutterman.

Topic: Translational Physiology

The American Journal of Physiology-Heart and Circulatory Physiology is soliciting the submission of original manuscripts in the field of Translational Physiology, an area of research that bridges the gap between basic physiology and patient care. Papers in this field may transfer clinical insights into hypotheses that can be tested and validated in the basic research laboratory, or they may transfer knowledge gained from basic research to human physiology or even to improved methods of treating or preventing disease.

The responding authors should indicate in their cover letter that the submitted manuscript is in response to this special call for papers. The manuscript will undergo normal peer review. If published, the article will be highlighted as part of the Translational Physiology Series.

If you have any questions or already have a manuscript in this area submitted to the American Journal of Physiology-Heart and Circulatory Physiology and would like to have it included for this series, please contact the Editor, Dr. David R. Harder (Phone, 414-456-5613; Fax, 414-456-6515).